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Hydrocarbon-stapled peptides are covalently constrained alpha-helical peptidomimetics, synthesized by substitution of two strategically spaced residues with terminal olefin-containing unnatural amino acids, followed by ring-closing olefin metathesis (RCM) to cyclize the peptide

The most frequent genetic event in giant CMNs are NRAS mutations (up to 95%), which was discovered in one of our cases

Failing to label a vial with its reconstitution date makes it impossible to track how far into its stability window a given sample actually is

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People with higher levels of taurine have lower body mass index, lower blood pressure, and lower levels of dangerous lipids