IGF-1 is known to improve brain network dysconnectivity, a neurobiological feature of ASD (autism spectrum disorder)
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The supernatant was referred to as the low-molecular-weight fraction of the plasma
It could also reduce astrogliosis and microgliosis in the dentate gyrus region of the hippocampus, prevent the impairment of pro-opiomelanocortin and G-protein-coupled receptor 43 expression caused by T2D, and simultaneously increase the number of NeuN+ and GLP-1R neurons in the hippocampus [Reference de Paiva, da Silva, Mendona, de Souza and Peixoto53]
From days 1 to 15, rats received a daily dose of 0.8 mL of either MCT or LCT oil via intragastric gavage in the morning