Jane Smith, a nutrition expert, says, Vitamin B12 deficiency can show up in many ways
Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential
These include some heartburn medicines, including esomeprazole (Nexium), famotidine (Pepcid AC), lansoprazole (Prevacid), omeprazole (Prilosec OTC), pantoprazole (Protonix), rabeprazole (Aciphex), as well as some diabetes, gout, and chemotherapy drugs
For example, a study published in the Journal of Alternative and Complementary Medicine found that B12 supplements improved endurance and reduced fatigue in athletes
Figure 2: Changes in the histolopathological scores amongst the four experimental treatment groups