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Indeed, patients with T1DM present with increased GFR (2550%), glomerular hypertrophy and increased kidney size during the early course of the disease, which may promote the development of diabetic nephropathy [193, 194]
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Measured GPX activities in the plasma (GPX3) or blood cells (GPX1 and GPX4) can be used as better biomarkers of the functional Se status
Unlike oral supplements, which are limited by digestion and absorption in the gut, intravenous administration allows significantly higher levels of vitamin C to circulate through the body in a controlled clinical setting
