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Inhibition of SGLT2 emerges as a potential approach for NAFLD/NASH treatment both by reduction of hyperglycemia and body weight and, possibly, through reduction of oxidative stress and inflammation

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10.1038/nrneph.2016.145 44

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Originally approved for diabetes, GLP-1 drugs are positively used in the management of weight loss, cardiovascular risk, fatty liver disease, and neurodegenerative conditions

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But B12 is involved in complex body wide set of interactions

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The Growing Obesity Crisis and Treatment Landscape Obesity is a chronic metabolic disease characterized by excessive body fat accumulation and is associated with a higher risk of cardiovascular disease, type 2 diabetes (T2D), and cancer

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