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10.1016/j.bcp.2010.04.004 Biochem
Coya said the trial met its primary endpoint for safety and secondary endpoint for regulatory T cell (Treg) cell population enhancement, with no off-target effects on T effector lymphocytes, providing further evidence of target engagement in 22 patients dosed with five days of LD IL-2 (106 IU/day) or placebo every four weeks for 21 weeks
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