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Na YJ, Choi KJ, Jung WH, Park SB, Kang S, Ahn JH, et al
It binds to a series of receptors known as melanocortin receptors (MCRs)
These products work by reducing melanin production, aiming to lighten the skin
In the STEP 1 and STEP 2 trials, sex was self-reported
Even small amounts of degradation products or synthesis impurities can introduce unintended receptor interactions or background signaling activity that complicates interpretation in receptor binding assays, metabolic pathway studies, and cell-based experiments
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