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The observed lack of a significant accumulation of PHN in brain following the intraventricular administration of (+)-amphetamine and the formation of appreciable amounts of PHN from (+)-POH in brain tissue in vivo supports the view that the aromatic hydroxylation of amphetamine following its systemic administration occurs predominantly in the periphery, and that POH is then transported through the blood-brain barrier, taken up by noradrenergic neurones in brain where (+)-POH is converted in the storage vesicles by dopamine -hydroxylase to PHN

Indeed, lifestyle nutritional interventions should be thought of only as temporary solutions and continued emphasis must be placed on eliminating lead in childrens environments in the first place

Even when refrigeration is suggested, proper sealing and single-dose handling are still important

& Crabb, D

Gonzalez says