Pay in 4 interest-free payments of $6.91 Learn more
Ships within 48 hours · Estimated delivery Aug 8 - Aug 13
Spironolactone Class * Potassium-sparing diuretic * Aldosterone (mineralocorticoid) receptor antagonist Mechanism of Action Spironolactone blocks aldosterone receptors in the distal convoluted tubule and collecting duct, resulting in: * Increased sodium and water excretion * Reduced potassium excretion (potassium retention) * Reduced cardiac and vascular remodeling in heart failure Indications * Heart failure with reduced ejection fraction (HFrEF) * Resistant hypertension * Primary hyperaldosteronism (Conn syndrome) * Ascites due to liver cirrhosis * Edema associated with heart failure or nephrotic syndrome * Polycystic ovary syndrome (PCOS) for hirsutism * Prevention of hypokalemia Dosage Adults * Heart failure: 12.525 mg once daily, titrated as needed * Ascites: 100400 mg daily * Hypertension: 25100 mg daily Adverse Effects Common * Hyperkalemia * Nausea * Dizziness * Fatigue Endocrine Effects * Gynecomastia * Breast tenderness * Erectile dysfunction * Decreased libido * Menstrual irregularities Contraindications * Hyperkalemia * Severe renal impairment * Addison disease * Hypersensitivity to spironolactone Drug Interactions * ACE inhibitors * ARBs * Potassium supplements * Other potassium-sparing diuretics These combinations increase the risk of hyperkalemia
Our program anchors the medicine to healthy habitsprotein, fiber, hydration, sleep, and simple activityso the biology we unlock actually shows up on the scale and in how your clothes fit
Antioxidants may therefore offset oxidative stress by removing free radicals
The microtiter plate provided in this kit has been pre-coated with GSH
However, Dihexa remains entirely preclinical, and its foundational research has faced serious integrity concerns including an expression of concern and a retraction on key papers
US$ 23.58
US$ 29.43
US$ 20.74
US$ 22.49
US$ 20.82
US$ 29.63
US$ 26.12
