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Hao L, Zhong W, Dong H et al (2021) ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis
It acts as a targeted antioxidant there, protecting against the oxidative damage that degrades mitochondrial efficiency over time
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L-Buthionine sulphoximine (BSO), which inhibits gamma glutamyl cysteine synthetase (GCS), was used to modulate the cellular redox status
104 PanL.XieL.YangW.FengS.MaoW.YeL.et al (2025)
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