doi: 10.1016/j.jcjd.2019.09.003 110 HusainMBirkenfeldALDonsmarkMDunganKEliaschewitzFGFrancoDRet al
Copper complexes, such as the Hinokitiol copper complex, inhibit the deubiquitinase activity of certain proteasomes, contributing to ATF4-associated ER stress and subsequently to paraptosis [147]
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Instead, approved interventions are stratified according to a patient's body mass index (BMI), the presence of weight-related health conditions, and their individual clinical circumstances