Very important and practically oriented paper Nice overview of advantages and limitations A must read for anybody who treats these patients To view or add a comment, sign in GLP-1RAs Show Significant Liver and Metabolic Benefits in MASLD A new systematic review and meta-analysis of 32 randomized controlled trials reveals that GLP-1 receptor agonists (GLP-1RAs) significantly improve liver and metabolic outcomes in patients with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD), far outperforming DPP-4 inhibitors, which showed minimal effects beyond glycemic control
The dose-dependent nature of semaglutide-associated nodules, documented in the first published case report, suggests that dose reduction may resolve the problem when nodules occur repeatedly
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Over about two years, GLP-1 use was tied to a 41% lower rate of obesity-related cancers overall, and endometrial cancer, one of the most weight-driven cancers there is, dropped by 58%
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