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10.3810/pgm.2009.11.2079 141 PalmerS
Symptoms such as nausea, fatigue, constipation, or diarrhea occur because the medication slows digestion and alters appetite signaling
Getty-Kaushik L et al (2006) Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification
Via the vagus nerve, gastrointestinal GLP-1 production stimulates the Arc and PVN in the hypothalamus as well as the NTS and area postrema, a locus of central nausea
If it is left out, however, Zepbound is only good for 21 days once it reaches room temperature
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