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Figure 1 Biosynthesis and Redox Regulation The biosynthesis of GSH occurs in a two-step reaction involving two adenosine triphosphate (ATP) molecules catalyzed by two enzymes, namely, -glutamylcysteine synthetase (-ECS) and glutathione synthetase (GSHS)

Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF)

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