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The researchers assessed the change in body weight from baseline within each trial and subgroup and they also carried out a mediation analysis to differentiate between direct and indirect effects of semaglutide on weight loss, the latter of which was mediated by nausea or vomiting

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The drugs benefits are clear, but their vast benefits could also be a double-edged sword

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& Mruk, D

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And the evidence connecting them to GLP-1 medications has grown substantially over the past two years

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Combining semaglutide with an active lifestyle leads to quicker and more sustainable results

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