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The first GLP-1 analog, exenatide (Byetta), lowering blood pressure exerting cardioprotective effects reducing body weight This last effect led to the study and ultimate approval of some GLP-1 analogs as an obesity treatment

GLP-1 receptor signaling pathways

Basilia Zingarelli, Cincinnati Childrens Hospital Medical Center, United States Updates Copyright 2023 Mehdi, Pusapati, Anwar, Lohana, Kumar, Nandula, Nawaz, Tracey, Yang, LeRoith, Brownstein and Roth

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Biochemistry (Mosc.) 81 (5): 465480