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The result of his insight would eventually reshape the treatment of metabolic disease worldwide, leading to a class of drugs that now includes Ozempic, Wegovy, Mounjaro, and Zepboundmedications that have been called the most important advance in metabolic health since insulin itself

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Moreover, it promotes insulin release from the pancreas, inhibits glucagon secretion, and affects areas of the brain that control hunger

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Clinical Rationale for Early AOM Intervention Traditional obesity management often follows a fixed-duration behavioral therapy (BT) approach before considering medication, yet mounting evidence suggests this may not be optimal for many patients