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The trial will randomise patients with IIH to determine the efficacy and safety of Presendin versus placebo
48 GSH levels were determined within the volume of interest using MEGA-PRESS double-editing for the cysteinyl -CH 2 residue of GSH 7 (repetition time=2,000 ms, echo time=122 ms, free induction decay points=2,048, spectral width=2,000 Hz, number of averages=8 per phase cycle ON or OFF, 320 acquisitions total requiring just under 11 min)
Co-immunoprecipitation studies demonstrated that the peptide reduces eNOS/caveolin-1 binding by approximately 50%, effectively doubling the available eNOS for nitric oxide production
4 AntonucciF.CorradiniI.FossatiG.TomasoniR.MennaE.MatteoliM
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