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Patients whose primary goal is maximum weight loss and who want the drug with the strongest efficacy data Those who have plateaued on semaglutide and need a more potent treatment Adults with obesity and obstructive sleep apnea (the only FDA-approved pharmacotherapy for OSA) Type 2 diabetes patients who need stronger HbA1c reduction beyond what semaglutide can provide Patients for whom insurance covers tirzepatide at comparable or lower cost to semaglutide Who should choose semaglutide
Pagano G, Manfredi C, Pallard FV, Lyakhovich A, Tiano L, Trifuoggi M (2021) Potential roles of mitochondrial cofactors in the adjuvant mitigation of pro-inflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia
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Some people report increased hunger in the days before their next weekly retatrutide dose, which may reflect declining plasma drug concentrations
