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In clinical trials, the most common adverse effects were gastrointestinal, including nausea, vomiting, diarrhea, and constipation

We could also see a slowing demand for the obstructive sleep apnea market, which includes a range of products such as continuous positive airway pressure (CPAP) devices

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Interestingly, the mTORC1 signaling pathway plays a pivotal role in this adaptive metabolic reprogramming, especially under glutamine-restricted conditions

Talazoparib and ZEN003694 (a BET inhibitor) are being evaluated in an ongoing phase II clinical trial (NCT05327010) for recurrent PARPi-resistant cancer