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Suicide attempts and major depression were reported as serious adverse events (SAEs) (with no external adjudication) in a large number of RCTs (Table 1)

A: Observational research suggests that people taking GLP-1 receptor agonists may have a lower risk of developing substance use disorders, but clinical trials are needed to confirm whether these drugs directly influence addiction

New England Journal of Medicine , NEJMoa2511774

10.1007/s12032-015-0633-8 43

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