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Overall, the most common symptoms of pernicious anemia are fatigue (55%), loss of sensation in limbs (32%), excessive weight loss (27%), and a sore tongue (23%) (221)

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Dyspepsia, characterized by upper abdominal discomfort, early satiety, or postprandial fullness, may affect a similar proportion of patients and can contribute to reduced caloric intake and weight loss, though it may also impact quality of life if severe or persistent