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Methimazole is an oral antithyroid drug that has recently attracted attention due to its depigmenting effect by inhibiting peroxidase, but it has also been shown to exert inhibitory effects on tyrosinase in experimental studies
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however, it is highly recommended to conduct a patch test prior to regular application of skincare products
users often dose it lower or less often than the unmodified form
The drug reduces hepatic glucose production, enhances glucose uptake in the peripheral tissues and increases insulin sensitivity 115
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