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Contact your healthcare provider for severe or worsening fatigue interfering with daily activities, fatigue accompanied by dizziness, chest pain, severe nausea, inability to keep down fluids for over 24 hours, dark urine, severe abdominal pain, or signs of allergic reaction

doi:10.1126/science.287.5453.664 67

In a yearlong Phase 3 trial, the highest dose of Lilys pill, orforglipron, lowered a measure of blood sugar called A1C by 1.9 percentage points, while the highest dose of Novos drug, marketed as Rybelsus, lowered A1C by 1.5 percentage points, when analyzing all patients regardless of discontinuations

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