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GLP-1 receptor agonists have been shown in multiple studies to exert anti-inflammatory effects, including inhibition of monocyte chemotaxis, suppression of macrophage inflammatory responses, and AMPK-mediated downregulation of the NF-B signaling pathway, thereby reducing systemic inflammation (36)

Annals of dermatology, 36(6), 384388

Finally, we note that the model predicts modest decreases in the rate of the DNA methylation reaction (vDNMT) and this is consistent with the reported global DNA hypomethylation seen in autistic children [73]