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Unlike traditional weight loss medications, Tirzepatide is a dual GIP and GLP-1 receptor agonist , meaning it targets two powerful hormonal pathways that control appetite, digestion, and blood sugar
However, research on liraglutide, including a 31-study meta-analysis of over 8,000 patients, has shown that injection of GLP-1 agonists stimulates the same effect on the vagus nerve whether stomach tissue is distended or not
Diabetologia 63:221228
This is typically when people take comparison photos and realize how much has changed
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