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In contrast, in AMYRs bound to rAmy 15 or the pramlintide analogue, San385 16 , an Asn at the equivalent peptide position (N14 rAmy ) adopts an upward rotamer that is exposed to the solvent environment and forms a H-bond with the backbone of L291 ECL2 (Fig
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Recognizing this distinction matters
The kidney filters these metabolites from the blood, excreting them into the urine
Unlike many medical conditions, NAION has no effective treatment available, making the vision loss permanent in nearly all cases
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