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Given the increasing evidence of alternative receptor-independent sources of cAMP (from intracellular sAC) (29, 30), we hypothesized that GLP-1(2836) mediates its GLP-1Rindependent effects through sAC
doi: 10.1111/cbdd.13915 61 HaKBSangartitWJeongARLeeESKimHMShimSet al
However, in states of activation, including oncogenesis, B cell activation depends on G6PD and PPP activity to mitigate oxidative stress (65), and the hypermetabolic leukocytes of acute B-cell leukemia are likewise more sensitive to oxidant stressors, such as dihydroartemisinin (66)
Although neither kinase was predicted to phosphorylate S114 directly, a highly conserved sequence neighboring S114 was strongly predicted to be CSNK11 (KIN-19) phosphorylation sites (Supplementary Fig
Yuan C, Babic A, Khalaf N, et al
