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PMCID: PMC8385392 ) Kyriakos G, Diamantis E, Memi E, Elefsiniotis I (2022) An uncommon case of dulaglutide-related morbilliform drug eruption

The FDA prescribing information notes that tirzepatide can reduce the exposure to oral contraceptives, requiring the use of backup contraception for 4 weeks after initiation and after each dose escalation of tirzepatide

One possibility is that GLP-1R endocytosis is required for agonist uptake by the brain via hypothalamic tanycytes, as described for leptin 65

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Care for chronic conditions such as obesity relies on the medical home: a concept of comprehensive and strategic coordination among multiple providers, such as weight management specialists, behavioral health experts, nutritionists, and primary care, to provide long-term care to patients as they transition from childhood to adolescence and adulthood