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Canadian Regulatory Context BPC-157 is not approved by Health Canada for human therapeutic use

Phase 2b completed in T2D) Status: Investigational not approved by FDA or EMA Heres what makes it different from everything else on the market and in the pipeline: - Semaglutide (Ozempic/Wegovy/Rybelsus): GLP-1 only - Tirzepatide (Mounjaro/Zepbound): GLP-1 + GIP - Retatrutide (investigational): GLP-1 + GIP + Glucagon - Amycretin : GLP-1 + Amylin Different receptor pairing

When combined with semaglutide in CagriSema, the glycemic improvements were substantial

The key difference is that retatrutide provides triple agonism (GLP-1 + GIP + glucagon) while semaglutide provides only GLP-1 agonism

We are pleased to share that Nikkei Online has featured the collaboration between NB Health Laboratory (NBHL) and FRONTEO