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In cells, the presence of MTs confers resistance to the harmful effects of Cd, but the inability to produce MTs makes cells more susceptible to the metals effects (53)

Caloric restriction mimicry: Some investigators have noted that the metabolic effects of glutathione repletion in older adults improved insulin sensitivity, reduced inflammation, enhanced mitochondrial function overlap substantially with known benefits of caloric restriction, suggesting that glutathione deficiency may partly mediate the metabolic decline of aging [10][11]

A diet that is low in the amino acid lysine and high in the amino acid arginine can lead to all these problemsand more

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