In obese wild-type mice, chronic experimental exposure was associated with reduced body weight and body fat, increased lipolytic sensitivity, and increased beta-3-adrenergic-receptor RNA expression in adipose tissue
General guidelines suggest individuals under 150 pounds may start with 50-75mg daily, those between 150 and 200 pounds typically use 75mg daily as a standard protocol, and individuals over 200 pounds may need 75-100mg daily for optimal effects
On a molecular level, AOD-9604 is compact enough to achieve good solubility in aqueous diluents yet large enough to retain the structural motif needed for its adipocyte-targeting activity
The research, published in the Journal of Endocrinology and Metabolism, found that the peptide had no effect on serum IGF-1 levels, no negative effect on carbohydrate metabolism, and no anti-AOD-9604 antibodies were detected in any patients
How Safe Is Frequent B12 Use