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Summary: Osmotic laxatives such as macrogol (Movicol, Laxido) or bulk-forming laxatives like ispaghula husk (Fybogel) are generally preferred first-line treatments for GLP-1-related constipation in the UK
Recommended sites include the abdomen (avoiding a 2-inch radius around the navel), anterior and lateral thigh, and upper outer arm
Ozempic is the brand name for a medication called semaglutide and is part of a broad class of drugs known as GLP-1 agonists
The researchers found that among 334 patients receiving oral semaglutide at a 50 mg dose, three to nine patients experienced altered skin sensations including dysesthesias, hyperesthesia, neuralgia, pain of skin, paresthesia, sensitive skin, and skin burning sensation
Sci Rep 11(1):2275-
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