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It is likely that the amount of homocysteine generation from SAH and the amount of homocysteine conversion to cysteine via transsulfuration pathway was comparable, leading to unchanged homocysteine concentration in normal rats after Sal A treatment

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Observed in pilot human work A 2025 IV infusion pilot of BPC-157 in two adults at 10 mg and 20 mg reported no adverse effects on cardiac, hepatic, renal, thyroid, or glucose biomarkers (Lee et al., Alternative Therapies in Health and Medicine, 2025)