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Effect of liraglutide on the Janus kinase/signal transducer and transcription activator (JAK/STAT) pathway in diabetic kidney disease in db/db mice and in cultured endothelial cells
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Studies are needed to investigate the determinants of plasma tCys and the balance between its free and protein-bound fractions in humans, and whether cystine, given its associations with an unhealthy body fat distribution and lipoprotein profile, predicts cardiometabolic outcomes
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The plasma half-life under 30 minutes does not explain purported effects lasting hours to days
