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The scientific evidence for this is still developing, and many researchers find that the systemic effects from a subcutaneous injection are more than sufficient to target injuries anywhere in the body
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Negative evidence: A study in Indonesian individuals showed that supplementation with glutathione combined with vitamin C, alpha-lipoic acid, and zinc did not significantly lighten skin compared to placebo (Sitohang et al., J Clin Aesthet Dermatol, 2021) [63]
Structurally, they can be categorized into microcapsules, which consist of an API enclosed within a polymeric or lipid shell, and microspheres, in which the API is homogeneously distributed throughout the polymeric matrix [33, 34]
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