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References: Mercury and protein thiols: Stimulation of mitochondrial F1FO-ATPase and inhibition of respiration Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA Mercury has an affinity for the brain References: The Toxicology of Mercury and Its Chemical Compounds (Clarkson, Thomas, Magos, Laszlo, 2006) (a rather complete introduction to mercury toxicity) "The concentration in brain is about 5 times than in scalp hair about 250 times the corresponding concentration in blood" "Animal data including primates indicate that brain levels in the newborn may be as high as five times the corresponding levels in the mother" "Experimental work on rats has shown that methylmercury gains entry into the endothelial cells of the bloodbrain barrier as a complex with cysteine (Kerper et al., 1992

(2018) 31:e3914

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2.3 Repetitive elements and the circulome Repetitive elements comprise a substantial yet variable proportion of the circulomes studied to date

Addition of docosahexaenoic acid, but not arachidonic acid, activates glutathione and thioredoxin antioxidant systems in murine hippocampal HT22 cells: potential implications in neuroprotection