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Less common but clinically significant adverse effects include hypoglycaemia (particularly when used alongside insulin or sulphonylureas), acute pancreatitis, gallbladder disorders, and hypersensitivity reactions

Tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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if longer than 8 hours, contact your PlexusDx provider before your next injection to discuss whether the vial should be replaced