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Some challenges include: Side effects like nausea, constipation, or fatigue

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Absolute contraindications Medullary thyroid cancer MEN-2 Pregnancy or breastfeeding Prior severe allergic reaction to GLP-1 medications Conditions requiring extra caution Gastroparesis or delayed gastric emptying History of pancreatitis Advanced diabetic retinopathy Use alongside medications that increase hypoglycemia risk These and a few other situations require individualized assessment, which is why specialty endocrine care matters

Here, we confirm a robust improvement in glucose tolerance and insulin content (in direct proportion to -cell mass) as a result of exendin-4 treatment

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