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Additionally, P9 induces interleukin-6 (IL-6) secretion from the intestine, which subsequently stimulates GLP-1 secretion by intestinal L-cells and pancreatic -cells, and also affects Icam2 mRNA expression, which suggests the normal expression of Icam-2 and the effects of P9 in glucose homeostasis may require IL-6 [160] (Fig

doi: 10.1007/s11883-022-01062-2 26 MaXLiuZIlyasILittlePJKamatoDSahebkaAet al

Both tirzepatide and glutathione independently improve hepatic steatosis markers

Oral GLP-1 medications are now part of the treatment landscape, offering another way to support people affected by obesity

Patients should be advised that tirzepatide may delay gastric emptying, potentially affecting the absorption of oral medications