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PMID 24843404

This strategy leverages membrane biocompatibility to evade immune clearance (e.g., by macrophages) prior to reaching the target site, thereby minimizing immunogenicity [38, 39]

At therapeutic doses, gut absorption becomes the limiting factor IV delivery removes that ceiling

A kinetic study of -glutamyltransferase (GGT)-mediated S-nitrosoglutathione catabolism

Overall, five studies were defined as high quality (Reference Hassan, Alalfy and Hassan18,Reference Badawy, El Nashar and El Totongy20,Reference El Sharkwy and Abd El Aziz24,Reference Kose and Naziroglu26,Reference Ghomian, Khadem and Moeindarbari5)