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(7) and others (74, 75) have found that TMAO can increase platelet reactivity

SURMOUNT-2: tirzepatide with type 2 diabetes The second trial focused on adults who had both obesity and type 2 diabetes, a population that traditionally loses less weight with GLP-1 medications because insulin resistance and metabolic dysfunction create additional barriers

These include autoimmune conditions, Parkinson's disease, Alzheimer's disease, and cancer

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