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These data are a cornerstone in our research and build on our understanding of how MASH and cardiometabolic conditions like type 2 diabetes, obesity, dyslipidemia [abnormal fat levels in the blood], and high blood pressure are interrelated. Metabolic dysfunction-associated steatotic liver disease (MASLD), occurs when abnormal amounts of fat accumulate in the liver in the presence of cardiometabolic risk factors such as type 2 diabetes, obesity, high blood levels of cholesterol or other fats, or high blood pressure

Systemic exenatide treatment can reverse aging-associated transcriptomic changes in various brain cell types in mice, including glial and neurovascular cells