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Keywords: GLP-1 receptor agonist-related weight loss, massive weight loss, regenerative aesthetics, energy-based devices Introduction Approximately 1.9 billion people are considered overweight, and approximately 650 million adults have obesity

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The adipocyte-to-hepatocyte ratio in the liver significantly influences the hepatic function of gut intraepithelial cells, and lipid accumulation in hepatocytes is partially attributable to insulin resistance and macrophage-mediated adipocyte inflammation (Qi et al., 2024)

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