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AOD-9604 AOD-9604 is a peptide made from a modified fragment of human growth hormone (HGH)
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Research indicates that this peptide modulates angiogenesis through upregulation of vascular endothelial growth factor (VEGF) expression and enhancement of endothelial cell proliferation and migration
SURMOUNT-5 added another critical data point by directly comparing tirzepatide to semaglutide, which was previously considered the gold standard among GLP-1 agonists
This reinforces the need for carefully titrated regimens, especially in clinical settings where circadian timing (chronopharmacology) may dictate efficacy
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