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Many patients describe feeling younger overallnot surprising given that the therapy restores growth hormone patterns closer to those of youth

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Specifically, glutamate, a potentially neuroexcitotoxic compound, is thought to be the transmitter of the corticospinal tracts and certain spinal cord interneurons, therefore a systemic defect in its metabolism may contribute to motor neuron degeneration in ALS 30,31

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& Welsh, W

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Ethics declarations Conflict of interest The authors declare no competing interests

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