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Tamoxifen induced expression of p53 and p21(waf1/cip1), and stimulated G0-G1 phase cell cycle arrest [82]
Data availability All data needed to understand and assess the conclusions of this research are available in the main text, supplementary materials, the Disease-PERCEPTION portal ( and The raw gene expression datasets are publicly available and can be downloaded from GEO and ArrayExpress ( The identifiers for each of the studies are provided in Supplementary Data 1
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Generally, drops of more than 20 mmHg systolic or 10 mmHg diastolic warrant attention, particularly if accompanied by symptoms like dizziness or fatigue
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