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In week four, mice were initially trained for 10 min at a 5 inclination with a speed of 16 m/min, followed by an additional 40 min at a 10 inclination with the same speed

HR may remain unchanged or increase modestly because of competing direct chronotropic and reflex-mediated effects

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Ameliorative effect of rosiglitazone, a peroxisome proliferator gamma agonist on adriamycin-induced cardio toxicity via suppressing oxidative stress and apoptosis