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Key benefits Why people compare it 1 10 million times the synaptogenic potency of BDNF on a molar basis 2 Orally bioavailable peptidomimetic that crosses the blood-brain barrier 3 Promotes new dendritic spine formation in hippocampal CA1 neurons 4 Active at picomolar concentrations (10^-13 M) for cognitive enhancement 5 Reversed scopolamine-induced cognitive deficits in preclinical dementia models 6 Activates HGF/c-Met signaling via PI3K/Akt and Ras/MAPK cascades 7 Strengthens existing synaptic connections (long-term potentiation) 8 Protease-resistant design enables oral and subcutaneous administration Deep research About Dihexa Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a modified dipeptide analog with a molecular weight of approximately 507.63 Da
Free Radic Biol Med 49:16171628 Cooper AJL, Pulsinelli WA, Duffy TE (1980) Glutathione and ascorbate during ischemia and postischemic reperfusion in rat brain
Among these factors, dietary components, alterations in gastrointestinal microbiota, and autoimmune mechanisms have been proposed as potential contributors to ASD pathogenesis (Shaw et al
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