Many individuals may experience the most significant weight loss in the first few months
No human safety data exists
Historical bias in diagnostic criteria, lack of knowledgeable professionals, financial constraints, and other factors mean that many neurodivergent individuals, particularly women and people of color, may never receive formal diagnosis despite clearly meeting criteria
Common Side Effects and Short-Term Risks While GLP-1 weight loss drugs are often marketed as simple, powerful solutions, they can carry a long list of side effects, including: nausea, vomiting, loss of appetite, dizziness, infections, headache (a less common side effect, but still possible), mild tachycardia (increased heart rate), allergic reactions, hypoglycemia (blood sugar dropping too low), and kidney problems
I think eventually were going to need to do complication-specific clinical trials, as I mentioned, where its the improvement in the complication is the primary outcome measure, not amount of weight loss per se